Mu rwego rwo kugereranya ingaruka za NMNH na NMN, abashakashatsi bateye PBS na 250 mg / kg ya NMN naNMNHmu mbeba za C57BL / 6N, hanyuma zigakurikirana amaraso akurikirana. Ibisubizo byerekanye ko NMNH yongereye cyane urugero rwa NAD mu maraso, ku rugero runini kuruta NMN. NAD yapimwe ku ngingo zegeranijwe hakoreshejwe uburyo bwa enzyme cycle. Ibisubizo byerekanaga ko NMNH yongereye urwego rwa NAD mubice bitandukanye, kandi ingaruka zabaye nyinshi kurenza NMN. Byagize ingaruka zigaragara cyane ku mwijima no ku mpyiko, umwijima wiyongereyeho inshuro zirenga 5 naho impyiko ziyongera inshuro zirenga 5. Inshuro 2.
NMNH yongerewe mugihe cya reoxygenation, kandi hagaragaye ibimenyetso byerekana imvune yimpyiko KIM-1. Reoxygenation muri TEC yatumye ubwiyongere bukabije mu mvugo ya KIM-1, bwagabanutse cyane nyuma yo kuvurwa kwa NMNH, byerekana ko ubuyobozi bwaNMNHirashobora kugabanya neza kandi cyane kwangirika kwimpyiko zifata impyiko mugihe cya hypoxia na reoxygenation.
Inzira y'UbuzimaNMNHishoti ryukuri
Yibanze ku bucuruzi bwo guhinduranya imyaka myinshi
Igenzura cyane guhitamo ibikoresho fatizo no gushyiraho urufatiro rwo gutera
Ikizamini gisanzwe cyubushakashatsi, umusaruro mwiza
Epimedium ikuramo, turi abahanga
Isoko ryiza ryiza, murakaza neza kugirango mutange itegeko !!
